• Complete Genome Sequences of Seven Vibrio anguillarum Strains as Derived from PacBio Sequencing 

      Holm, Kåre Olav; Bækkedal, Cecilie; Johansson Söderberg, Jenny; Haugen, Peik (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-07)
      We report here the complete genome sequences of seven Vibrio anguillarum strains isolated from multiple geographic locations, thus increasing the total number of genomes of finished quality to 11. The genomes were de novo assembled from long-sequence PacBio reads. Including draft genomes, a total of 44 V. anguillarum genomes are currently available in the genome databases. They represent an important ...
    • Construction of a fur null mutant and RNA-sequencing provide deeper global understanding of the Aliivibrio salmonicida Fur regulon 

      Thode, Sunniva Katharina; Bækkedal, Cecilie; Söderberg, Jenny Johansson; Hjerde, Erik; Hansen, Hilde; Haugen, Peik (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-13)
      <i>Background:</i> The ferric uptake regulator (Fur) is a transcription factor and the main regulator of iron acquisition in prokaryotes. When bound to ferric iron, Fur recognizes its DNA binding site and generally executes its function by repressing transcription of its target genes. Due to its importance in virulence, the Fur regulon is well studied for several model bacteria. In our previous ...
    • The Spot 42 RNA: A regulatory small RNA with roles in the central metabolism 

      Haugen, Peik; Bækkedal, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-01)
      The Spot 42 RNA is a 109 nucleotide long (in Escherichia coli) noncoding small regulatory RNA (sRNA) encoded by the spf (spot fourty-two) gene. spf is found in gamma-proteobacteria and the majority of experimental work on Spot 42 RNA has been performed using E. coli, and recently Aliivibrio salmonicida. In the cell Spot 42 RNA plays essential roles as a regulator in carbohydrate metabolism and uptake, ...